After studying philosophy, she joined the Parisian cinema school La Fémis in 1986. Her student film, Cendrillon 90, was selected in various film festivals in Angers, Munich, and Montreal. She then worked as a screenwriter for filmmakers such as Mathieu Amalric and Emmanuel Salinger. In 2004, her film Blonde et Brune was nominated for the Best Short Film César Award. In 2008, she directed her first feature Les Inséparables. In 2019, she co-wrote with Stéphane Batut Burning Ghost which won the Jean-Vigo Prize. The Daughter of Albino Rodrigue is her second feature as a director.